Dr. Luther Swann (Ian Somerhalder) enters a world of untold horror when a mysterious disease transforms his best friend, Michael Fayne (Adrian Holmes), into a murderous predator who feeds on other humans. As the disease spreads and more people are transformed, society fractures into opposing camps pitting normal people against the growing number of these “vampires.” Swann races against time to understand what’s happening, while Fayne rises to become the powerful underground leader of the vampires.